6/17/2025

Tried, True and New

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Soybean Next Gen HT Combines Enlist® Technology with PPO Herbicide Tolerance

Expected in the early 2030s, a new, yet-to-be-named technology will take weed control to the next level.  For now, the scientists at Corteva Agriscience call it “Soybean Next Gen HT.” What promise does it hold for licensees and their farmer customers? Let’s take a look. 

Time-tested control against broadleaf weeds

Next Gen HT plot drone shot

PPO herbicides (Group 14) have been around for more than 60 years and continue to evolve with new classes of chemistry and modes of action. That’s one of the key reasons why scientists at Corteva are so excited about its future possibilities. Controlling broadleaf weeds in a broadleaf crop like soybeans has always been a challenge. For a long while, glyphosatetolerant soybeans were the solution. Now it’s Enlist E3® soybeans. What’s next? Soybean Next Gen HT. This new soybean trait stack is the result of a strategic collaboration between Corteva and BASF. It allows for post-emergent application of glyphosate, glufosinate, 2,4-D choline in Enlist® herbicides and PPO herbicides like BASF’s Kixor® and Tirexor® herbicides.   

The inclusion of PPO herbicide tolerance will give growers an additional mode of action to control weeds and manage herbicide resistance, a goal noted by Dr. Sam Eathington, Executive Vice President, Chief Technology and Digital Officer, Corteva Agriscience. “Expanding options for soybean farmers to manage weed challenges with the herbicides that work best for their operations is one of our priorities,” he stated. “We know farmers who prefer the Enlist® weed control system will need additional, new modes of action as they work to improve the sustainability of their weed-control practices.”

Soybean Next Gen HT will be a new option to fight both weeds and herbicide resistance. The Enlist weed control system, with tolerance to Enlist herbicides, glyphosate and glufosinate, paired with PPO tolerance, will create a powerful, dependable tool for farmers. And it’s just the start. Longer-term agreements between BASF and Corteva include plans to develop an additional soybean trait package that includes tolerance to glyphosate, glufosinate, Enlist herbicides, PPO herbicides and another, entirely new herbicide mode of action under development by BASF.

 

™ ® Trademarks of Corteva Agriscience and its affiliated companies. The transgenic soybean event in Enlist E3® soybeans is jointly developed and owned by Corteva Agriscience and M.S. Technologies L.L.C. Following burndown, Enlist Duo® and Enlist One® herbicides with Colex-D® technology are the only herbicides containing 2,4-D that are authorized for preemergence and postemergence use with Enlist® crops. Consult Enlist® herbicide labels for weed species controlled. Enlist Duo and Enlist One herbicides are not registered for use or sale in all states and counties; are not registered in AK, CA, CT, HI, ID, MA, ME, MT, NH, NV, OR, RI, UT, VT, WA and WY; and have additional subcounty restrictions in AL, GA, TN and TX, while existing county restrictions still remain in FL. All users must check “Bulletins Live! Two” no earlier than six months before using Enlist One or Enlist Duo. To obtain “Bulletins,” consult epa.gov/espp/, call 1-844-447-3813, or email ESPP@epa.gov. You must use the “Bulletin” valid for the month and state and county in which Enlist One or Enlist Duo are being applied. Contact your state pesticide regulatory agency if you have questions about the registration status of Enlist® herbicides in your area. ALWAYS READ AND FOLLOW PESTICIDE LABEL DIRECTIONS. IT IS A VIOLATION OF FEDERAL AND STATE LAW TO USE ANY PESTICIDE PRODUCT OTHER THAN IN ACCORDANCE WITH ITS LABELING. ONLY USE FORMULATIONS THAT ARE SPECIFICALLY LABELED FOR SUCH USE IN THE STATE OF APPLICATION. USE OF PESTICIDE PRODUCTS, INCLUDING, WITHOUT LIMITATION, 2,4-D-CONTAINING PRODUCTS NOT AUTHORIZED FOR USE WITH ENLIST CROPS, MAY RESULT IN OFF-TARGET DAMAGE TO SENSITIVE CROPS/AREAS AND/OR SUSCEPTIBLE PLANTS, IN ADDITION TO CIVIL AND/OR CRIMINAL PENALTIES. Additional product-specific stewardship requirements for Enlist crops, including the Enlist Product Use Guide, can be found at www.traitstewardship.com. Kixor® and Tirexor® are registered trademarks of BASF. © 2025 Corteva.   025755   LC (05/25)

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